Can I use SSO Authentication or Active Directory if I am using Smart Cache (FKA Turbo)?

Yes. Smart Cache (FKA Turbo) acts as a proxy for authentication requests from Desktop Apps and redirects them to CFS for authentication. Smart Cache (FKA Turbo) supports all CFS Single Sign-on authentication mechanisms. 

If Active Directory Authentication is enabled in CFS with an LDAP URL, users can be authenticated against AD.